Inactivated genotype 1 Japanese encephalitis vaccine for swine
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چکیده
منابع مشابه
Inactivated genotype 1 Japanese encephalitis vaccine for swine
PURPOSE Japanese encephalitis is a reproductive disorder caused by Japanese encephalitis virus (JEV) in swine. Recent genotype (G) shift phenomenon (G3 to G1) in the Asia-wide has posed a challenge for proper prevention by the current vaccine strain. Thus, new kinds of JEV G1 vaccines with enhanced immunogenicity have been required for pigs. MATERIALS AND METHODS Recombinant porcine granulocy...
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BACKGROUND Genotype I (GI) Japanese encephalitis virus (JEV) that replaced GIII virus has become the dominant circulating virus in Asia. Currently, all registered live and inactivated JEV vaccines are derived from genotype III viruses. In Taiwan, the compulsory JEV vaccination policy recommends that children receives four doses of formalin-inactivated Nakayama (GIII) JEV vaccine. METHODOLOGY/...
متن کاملJapanese Encephalitis Vaccine
clinic in preparation for a trip to Asia. They are then faced with the seemingly impossible decision of whether to spend money on a vaccine that has a rather bad reputation or to risk developing the disease, which would be much worse.1 Many of the physicians that have to advise them feel ill equipped to do so. From a Western perspective, JE is considered a rare and exotic disease, but for those...
متن کاملCurrent recommendations for the Japanese encephalitis vaccine.
Japanese encephalitis (JE) is a mosquito-borne flavivirus infection and an important cause of encephalitis in most of Asia and parts of the western Pacific. Most people infected with the JE virus (JEV) are asymptomatic or seemingly suffer from a nonspecific, flu-like illness; in others, JE can cause illness ranging from fever and headache to severe encephalitis. Although it can cause significan...
متن کاملLow Protective Efficacy of the Current Japanese Encephalitis Vaccine against the Emerging Genotype 5 Japanese Encephalitis Virus.
BACKGROUND The current Japanese encephalitis (JE) vaccine derived from G3 JE virus (JEV) can induce protective immunity against G1-G4 JEV genotypes. However, protective efficacy against the emerging G5 genotype has not been reported. METHODS/PRINCIPAL FINDINGS Using in vitro and in vivo tests, biological phenotype and cross-immunoreactions were compared between G3 JEV and G5 JEV (wild strains...
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ژورنال
عنوان ژورنال: Clinical and Experimental Vaccine Research
سال: 2014
ISSN: 2287-3651,2287-366X
DOI: 10.7774/cevr.2014.3.2.212